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Evaluation of Gafchromic ® EBT3 films characteristics in therapy photon, electron and proton beams

机译:评价Gafchromic®EBT3膜在治疗光子,电子和质子束中的特性

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摘要

Purpose: To evaluate the uncertainties and characteristics of radiochromic film-based dosimetry system using the EBT3 model Gafchromic ® film in therapy photon, electron and proton beams. Material and methods: EBT3 films were read using an EPSON Expression 10000XL/PRO scanner. They were irradiated in five beams, an Elekta SL25 6 MV and 18 MV photon beam, an IBA 100 MeV 5 × 5 cm 2 proton beam delivered by pencil-beam scanning, a 60 MeV fixed proton beam and an Elekta SL25 6 MeV electron beam. Reference dosimetry was performed using a FC65-G chamber (Elekta beam), a PPC05 (IBA beam) and both Markus 1916 and PPC40 Roos ion-chambers (60 MeV proton beam). Calibration curves of the radiochromic film dosimetry system were acquired and compared within a dose range of 0.4-10 Gy. An uncertainty budget was estimated on films irradiated by Elekta SL25 by measuring intra-film and inter-film reproducibility and uniformity; scanner uniformity and reproducibility; room light and film reading delay influences. Results: The global uncertainty on acquired optical densities was within 0.55% and could be reduced to 0.1% by placing films consistently at the center of the scanner. For all beam types, the calibration curves are within uncertainties of measured dose and optical densities. The total uncertainties on calibration curve due to film reading and fitting were within 1.5% for photon and proton beams. For electrons, the uncertainty was within 2% for dose superior to 0.8 Gy. Conclusions: The low combined uncertainty observed and low beam and energy-dependence make EBT3 suitable for dosimetry in various applications. © 2012 Associazione Italiana di Fisica Medica.
机译:目的:使用EBT3型Gafchromic®胶片在治疗光子,电子和质子束中评估基于放射性变色胶片的剂量测定系统的不确定性和特性。材料和方法:使用EPSON Expression 10000XL / PRO扫描仪读取EBT3胶片。它们以五束光束照射,分别为Elekta SL25 6 MV和18 MV光子束,IBA 100 MeV 5×5 cm 2质子束通过铅笔束扫描传输,60 MeV固定质子束和Elekta SL25 6 MeV电子束。 。参考剂量测定使用FC65-G室(Elekta束),PPC05(IBA束)以及Markus 1916和PPC40 Roos离子室(60 MeV质子束)进行。获取并在0.4-10Gy的剂量范围内比较了放射性变色膜剂量测定系统的校准曲线。通过测量胶片内和胶片间的再现性和均匀性,估算了用Elekta SL25辐照的胶片的不确定性预算。扫描仪的一致性和可重复性;室内光线和电影阅读延迟的影响。结果:获得的光学密度的整体不确定度在0.55%之内,并且可以通过将胶片始终放置在扫描仪的中央而降低到0.1%。对于所有类型的光束,校准曲线都在测量剂量和光密度的不确定性之内。对于光子和质子束,由于胶片的读取和拟合而导致的校准曲线的总不确定度在1.5%以内。对于电子,剂量高于0.8 Gy的不确定度在2%以内。结论:观察到的低综合不确定性以及低光束和能量依赖性使EBT3适用于各种应用中的剂量测定。 ©2012意大利医疗保险协会。

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